Pharmacist Salary in South Carolina (2026)
The average Pharmacist in South Carolina earns around $138,000/year. After taxes, your estimated take-home is $98,466/year ($8,206/month).
Take-Home Pay Breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $98,466 |
Monthly Take-Home Pay | $8,206 |
Biweekly Take-Home Pay | $3,787 |
Hourly Take-Home Pay based on 2,080 hrs/year | $47/hr |
Federal Tax | $21,854 |
State Tax | $7,123 |
FICA Taxes | $10,557 |
Effective Tax Rate total taxes ÷ gross salary | 28.65% |
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Pharmacist Salary Ranges in South Carolina
Not all Pharmacists earn the same — not even close
South Carolina's pharmacist market is anchored by MUSC Charleston pharmacy services (academic medical center pharmacy with substantial inpatient + outpatient + specialty pharmacy), Prisma Health pharmacy (largest SC health system across 17 hospitals + outpatient pharmacy network), Roper St. Francis Healthcare Charleston pharmacy, Bon Secours St. Francis Greenville pharmacy, AnMed Anderson + Spartanburg Regional + McLeod Florence community pharmacy, plus Publix + Walgreens + CVS + Harris Teeter retail pharmacy networks, with USC College of Pharmacy Columbia + MUSC College of Pharmacy Charleston academic training.
Senior Clinical Pharmacist (Hospital)
$128,000–$165,000
MUSC + Prisma + Roper + Bon Secours ICU + ED + oncology clinical pharmacy specialty
Senior Specialty Pharmacist
$118,000–$155,000
MUSC Hollings Cancer specialty pharmacy · oncology + transplant + HIV + REMS specialty
Senior Pharmacy Manager (Hospital)
$130,000–$175,000
Hospital pharmacy operations leadership · SC health system inpatient pharmacy
Senior Pharmacy Informatics
$118,000–$170,000
Epic Willow + Cerner pharmacy informatics · SC health system pharmacy IT
Senior Retail Pharmacist (Publix / Walgreens)
$112,000–$140,000
Retail pharmacy manager · Publix + Walgreens + CVS + Harris Teeter · senior retail band
Senior Ambulatory Care / MTM
$115,000–$150,000
MUSC + Prisma + Roper ambulatory pharmacy · MTM + anticoagulation + diabetes clinics
Senior Compounding / IV Pharmacy
$112,000–$148,000
SC hospital + 503A + 503B compounding · sterile + non-sterile · USP 797/800 specialty
Mid-Career Pharmacist (3-7 yrs)
$105,000–$130,000
Functional staff pharmacist at SC health system · transitioning to senior band
New Grad PharmD (0-2 yrs)
$95,000–$120,000
USC College of Pharmacy + MUSC College of Pharmacy PharmD pipeline · entry band
PGY-1 / PGY-2 Residency
$48,000–$58,000
MUSC + Prisma + Roper + Bon Secours pharmacy residencies · pre-clinical specialty path
Worth knowing: South Carolina operates two AVMA-accredited PharmD-granting institutions — USC College of Pharmacy Columbia (founded 1925, ~140 PharmD students/yr, the largest SC pharmacy school) + MUSC College of Pharmacy Charleston (founded 1881 as one of the oldest US pharmacy schools, ~85 PharmD students/yr) — and the dual-school pipeline supports the substantial SC retail + hospital + ambulatory pharmacy workforce that national pharmacist-career surveys understate. USC College of Pharmacy + MUSC College of Pharmacy combined graduate ~225 PharmDs/yr, supporting SC's pharmacy practice across Prisma Health + MUSC + Roper + Bon Secours health systems plus substantial retail pharmacy at Publix + Walgreens + CVS + Harris Teeter. MUSC Hollings Cancer Center pharmacy operates substantial oncology specialty pharmacy supporting MUSC's NCI-designated cancer center (the only NCI center in SC) — substantial chemotherapy + immunotherapy + cellular therapy pharmacy practice at academic medical center scale supporting senior specialty pharmacists at $118-155K TC. Publix Super Markets (the country's largest employee-owned supermarket chain with ~290 SC locations) operates substantial SC retail pharmacy — Publix's distinctive employee-ownership culture supports retail pharmacist retention. SC's 6.5% top bracket has limited impact on most pharmacist comp (most senior pharmacist comp lands $112-175K range below the top bracket). SC has 0% income tax up to $3,460 first bracket + RTW since 1954.
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More on South Carolina
Salaries by profession, top-paying roles by industry, and an economic breakdown for South Carolina in 2026.
Tax brackets, standard deductions, and take-home estimates for South Carolina in 2026.
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