How much does a Pharmacist make in South Carolina?

BLS puts the average Pharmacist pay in South Carolina at $136,730 a year (BLS, May 2025). On that pay in South Carolina, after federal taxes, FICA, and South Carolina state taxes, your estimated take-home pay is approximately $98,563 annually ($8,214/month).

What is the take-home pay for a Pharmacist in South Carolina?

On a $136,730 salary in South Carolina, your take-home pay is approximately $98,563/year or $8,214/month. Federal tax: $21,549. State tax: $6,158. FICA: $10,460.

Is $136,730 a good Pharmacist salary?

$136,730 is the BLS average Pharmacist pay in South Carolina, 3% below the US average of $140,920 (BLS, May 2025). The middle 50% in South Carolina earn between $126,790 and $158,210.

How do South Carolina taxes affect Pharmacist salaries?

South Carolina levies state income tax on top of federal taxes. Your estimated state tax on $136,730 is $6,158. Your total effective tax rate is approximately 27.9%.

What are the career growth prospects for Pharmacists?

In South Carolina, the top 10% earn over $170,270 and the bottom 10% under $82,430 (BLS, May 2025). 3% growth through 2032 (about as fast as average). Related roles include: Clinical Pharmacist, Retail Pharmacist, Hospital Pharmacist, Pharmacy Technician.

How can a Pharmacist in South Carolina reduce their tax bill?

Maximize your 401(k) contribution ($24,500 in 2026) to reduce taxable income. An HSA ($4,400 single / $8,750 family) adds further pre-tax savings. These strategies can save thousands annually — use our calculator to see your exact savings.

Healthcare

Pharmacist Salary in South Carolina (2026)

Average Pharmacist pay in South Carolina

$136,730/year

≈ $66/hour before tax

Middle 50% earn $126,790–$158,210

US average: $140,920

Source: BLS, May 2025

After tax (single filer)

$98,563/year

$8,214/month · effective tax rate 27.91%

Federal $21,549
State $6,158
FICA $10,460
Take-home

Pay by role in South Carolina

Senior / Specialist Pharmacist / Clinical Specialist / Pharmacy ManagerBLS · 75th–90th percentile$158,210–$170,270
Staff Pharmacist (hospital, retail, specialty)BLS · middle 50%$126,790–$158,210
New Graduate PharmacistBLS · 10th–25th percentile$82,430–$126,790

See the full tax breakdown

Category	Amount
Annual Take-Home Pay	$98,563
Monthly Take-Home Pay	$8,214
Biweekly Take-Home Pay	$3,791
Hourly Take-Home Pay based on 2,080 hrs/year	$47/hr
Federal Tax	$21,549
State Tax	$6,158
FICA Taxes	$10,460
Effective Tax Rate total taxes ÷ gross salary	27.91%

Estimates only — not tax advice. · Full disclaimer →

Not all Pharmacists earn the same — not even close

South Carolina's pharmacist market is anchored by MUSC Charleston pharmacy services (academic medical center pharmacy with substantial inpatient + outpatient + specialty pharmacy), Prisma Health pharmacy (largest SC health system across 17 hospitals + outpatient pharmacy network), Roper St. Francis Healthcare Charleston pharmacy, Bon Secours St. Francis Greenville pharmacy, AnMed Anderson + Spartanburg Regional + McLeod Florence community pharmacy, plus Publix + Walgreens + CVS + Harris Teeter retail pharmacy networks, with USC College of Pharmacy Columbia + MUSC College of Pharmacy Charleston academic training.

Senior / Specialist Pharmacist / Clinical Specialist / Pharmacy Manager

$158,210–$170,270

MUSC + Prisma + Roper + Bon Secours ICU + ED + oncology clinical pharmacy specialty

Source: BLS May 2025 · Pharmacists · South Carolina · 75th–90th percentile

Staff Pharmacist (hospital, retail, specialty)

$126,790–$158,210

Functional staff pharmacist at SC health system · transitioning to senior band

Source: BLS May 2025 · Pharmacists · South Carolina · middle 50%

New Graduate Pharmacist

$82,430–$126,790

USC College of Pharmacy + MUSC College of Pharmacy PharmD pipeline · entry band

Source: BLS May 2025 · Pharmacists · South Carolina · 10th–25th percentile

Worth knowing: South Carolina operates two AVMA-accredited PharmD-granting institutions — USC College of Pharmacy Columbia (founded 1925, ~140 PharmD students/yr, the largest SC pharmacy school) + MUSC College of Pharmacy Charleston (founded 1881 as one of the oldest US pharmacy schools, ~85 PharmD students/yr) — and the dual-school pipeline supports the substantial SC retail + hospital + ambulatory pharmacy workforce that national pharmacist-career surveys understate. USC College of Pharmacy + MUSC College of Pharmacy combined graduate ~225 PharmDs/yr, supporting SC's pharmacy practice across Prisma Health + MUSC + Roper + Bon Secours health systems plus substantial retail pharmacy at Publix + Walgreens + CVS + Harris Teeter. MUSC Hollings Cancer Center pharmacy operates substantial oncology specialty pharmacy supporting MUSC's NCI-designated cancer center (the only NCI center in SC) — substantial chemotherapy + immunotherapy + cellular therapy pharmacy practice at academic medical center scale supporting senior specialty pharmacists at $118-155K TC. Publix Super Markets (the country's largest employee-owned supermarket chain with ~290 SC locations) operates substantial SC retail pharmacy — Publix's distinctive employee-ownership culture supports retail pharmacist retention. SC's 5.21% top rate (H.4216, 2026) applies above $30,000 of SC taxable income, so it reaches nearly all pharmacist comp; the first $30,000 is taxed at 1.99%. SC has been RTW since 1954.

Sources & Methodology

Salary figures are market estimates for Pharmacists in South Carolina and vary by employer, specialty, seniority, and metro. Take-home math assumes a single filer with no dependents, the standard deduction, and South Carolina 2026 state rates. Local taxes, insurance premiums, and pre-tax contributions will move your number — run the calculator for your own situation.

Run your own numbers