Nurse Practitioner Salary in South Dakota (2026)
The average Nurse Practitioner in South Dakota earns around $138,000/year. After taxes, your estimated take-home is $105,589/year ($8,799/month).
Take-Home Pay Breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $105,589 |
Monthly Take-Home Pay | $8,799 |
Biweekly Take-Home Pay | $4,061 |
Hourly Take-Home Pay based on 2,080 hrs/year | $51/hr |
Federal Tax | $21,854 |
State Tax | $0 |
FICA Taxes | $10,557 |
Effective Tax Rate total taxes ÷ gross salary | 23.49% |
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Nurse Practitioner Salary Ranges in South Dakota
Not all Nurse Practitioners earn the same — not even close
South Dakota's nurse practitioner market is anchored by SD NP Full Practice Authority since 2017 (SDCL Title 36 + 2017 HB 1080 + the substantial SD NP independent practice + the substantial SD NP rural + tribal NP practice + the substantial SD NP own clinic ownership), Sanford Health Sioux Falls (largest SD-HQ multi-state ~50K + ~46 hospitals + Sanford USD Medical Center + Sanford Children's Hospital + Sanford Castle of Care telehealth NP), Avera Health Catholic (Avera McKennan + Avera Heart Hospital + Avera Cancer Institute + Avera eCARE telemedicine), Monument Health Rapid City Western SD, the substantial Indian Health Service IHS SD reservation NP (Pine Ridge + Rosebud + Cheyenne River + Standing Rock + Yankton + Sisseton-Wahpeton IHS + Crow Creek + Lower Brule IHS + the substantial SD reservation NP + IHS Loan Repayment Program + IHS Scholarship), plus USD College of Nursing DNP + SDSU DNP NP pipelines.
Senior NP Owner / Independent Practice
$115,000–$185,000+ profit
SD FPA since 2017 · NP own primary care + women + mental health clinic ownership
Senior FNP (Sanford / Avera / Monument)
$98,000–$138,000+ bonus
Family NP at Sanford + Avera + Monument + community health · panel-based primary care
Senior Acute Care NP (Sanford USD / Avera)
$105,000–$148,000+ bonus
AGACNP at Sanford USD Level 1 + Avera McKennan + Monument · acute care
Senior PMHNP (Mental Health)
$108,000–$158,000+ bonus
PMHNP at Sanford + Avera Behavioral Health + the substantial SD psychiatric NP demand
Senior Pediatric NP (Sanford Children)
$98,000–$138,000+ bonus
PNP at Sanford Children Hospital Sioux Falls · the substantial SD pediatric NP
Senior IHS Reservation NP
$108,000–$148,000+ loan repayment + housing
Pine Ridge + Rosebud + Cheyenne River + Standing Rock IHS · NHSC + LRP + housing
Senior Rural NP (Western SD / Black Hills)
$98,000–$138,000+ loan repayment
Rural NP at Western SD + Black Hills + Sioux Empire · NHSC + SD Loan Repayment
Senior Federal Civilian NP (VA Sioux Falls)
$108,000–$148,000
VA Sioux Falls + Fort Meade + Hot Springs VA · GS-13 federal civilian NP
Senior Avera eCARE Telemedicine NP
$95,000–$135,000+ bonus
Avera eCARE telemedicine · the substantial Avera nationwide telemedicine NP
New NP (0-2 yrs)
$82,000–$108,000
New grad NP at Sanford + Avera + Monument residency programs · entry NP band
Worth knowing: South Dakota NP Full Practice Authority since 2017 + Indian Health Service SD reservation NP + Avera eCARE telemedicine NP is one of the country's distinctive concentrated US single-state FPA + IHS + telemedicine NP anchor and a feature most national NP surveys understate for SD. SD NP FPA (SDCL Title 36 + 2017 HB 1080 + the substantial SD NP independent practice authority since 2017 + the substantial SD NP own clinic ownership + the substantial SD NP independent prescribing + the substantial SD NP independent diagnosis + treatment + the substantial SD NP rural + tribal + community health independent practice serving Western SD + Sioux Empire + the substantial SD reservation NP) supports distinctive SD NP independent practice economics. Senior independent NP clinic owners clear $115-185K+ profit. The substantial Indian Health Service IHS SD reservation NP (Pine Ridge IHS as one of country's largest US IHS hospitals + Rosebud + Cheyenne River + Standing Rock + Yankton + Sisseton-Wahpeton + Crow Creek + Lower Brule + IHS Loan Repayment Program LRP + IHS Scholarship Program + housing allowance) supports substantial SD IHS NP. Avera eCARE telemedicine NP (the substantial Avera eCARE substantial nationwide telemedicine NP + the substantial Avera eCARE Pharmacy + Behavioral Health + ICU + ED telemedicine) supports distinctive SD telemedicine NP. Sanford + Avera + Monument + Sanford Children + VA Sioux Falls federal civilian NP. SD 0% state income tax + SD RTW since 1946 anchor the SD NP proposition.
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More on South Dakota
Salaries by profession, top-paying roles by industry, and an economic breakdown for South Dakota in 2026.
Tax brackets, standard deductions, and take-home estimates for South Dakota in 2026.
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