Healthcare

Nurse Practitioner Salary in Oklahoma (2026)

The average Nurse Practitioner in Oklahoma earns around $138,000/year. After taxes, your estimated take-home is $99,665/year ($8,305/month).

Take-Home Pay Breakdown

CategoryAmount
Annual Take-Home Pay
$99,665
Monthly Take-Home Pay
$8,305
Biweekly Take-Home Pay
$3,833
Hourly Take-Home Pay

based on 2,080 hrs/year

$48/hr
Federal Tax
$21,854
State Tax
$5,924
FICA Taxes
$10,557
Effective Tax Rate

total taxes ÷ gross salary

27.78%
Estimates only — not tax advice. · Full disclaimer →

Want to model 401(k), HSA, or pre-tax contributions against your full salary? Open the salary calculator

Got a year-end bonus, sign-on, or retention payout? See the bonus calculator

1099 contract work or side gigs? Self-employment tax adds 15.3% on top. Open the 1099 tax calculator

Working overtime? The 2025 OBBBA deduction may save you up to $12,500 on federal tax. Open the No Tax on Overtime calculator

Key terms:···

Nurse Practitioner Salary Ranges in Oklahoma

Entry Level (0–3 yrs)

$110,000

/year

See tax breakdown →

Mid Level (3–7 yrs)

$138,000

/year

See tax breakdown →

Senior Level (7+ yrs)

$220,000

/year

See tax breakdown →

Not all Nurse Practitioners earn the same — not even close

Oklahoma's nurse practitioner market is anchored by OU Health Sciences Center Oklahoma City (~14K academic medical center with substantial APP integration), Integris Health Oklahoma City (~12K largest OK health system with APP-led primary care), Saint Francis Health System Tulsa (~10K, NE OK academic + tertiary), Mercy Hospital OKC, plus substantial tribal health system APP-led primary care (Cherokee Nation Health Services + Chickasaw Nation + Choctaw Nation operating substantial NP-led rural clinics across the 14-county Cherokee Nation reservation + Chickasaw Nation reservation + Choctaw Nation reservation), OU College of Nursing + OSU College of Nursing DNP pipelines. OK requires collaborative practice agreement with physician — OK is a hybrid framework state.

Senior Specialty NP (Cardiology / Oncology)

$118,000–$180,000

OU + Integris + Saint Francis cardiology + oncology + transplant NP · OK collaborative required

Senior Psychiatric Mental Health NP

$115,000–$175,000

OU Psychiatry · Griffin Memorial Hospital · PMHNP · OK PsyPact telehealth since 2020

Senior Acute Care NP (ICU / ED)

$112,000–$170,000

OU Level 1 · Hillcrest Tulsa Level 1 · OU Critical Care · ACNP-AG subspecialty band

Senior Hospitalist NP

$110,000–$165,000

OU + Integris + Saint Francis + Mercy hospital medicine APP · day + nocturnist mix

Senior Primary Care NP (Family Medicine)

$95,000–$140,000

Integris + Saint Francis + Mercy · OK collaborative required for prescriptive authority

Senior Pediatric NP

$92,000–$135,000

Oklahoma Children's · The Children's Hospital Saint Francis · CPNP-PC + CPNP-AC

Senior Women's Health NP

$92,000–$130,000

OU WHNP · Saint Francis WomenCare · WHNP-BC

Senior Tribal Health NP (Cherokee / Chickasaw)

$95,000–$140,000

Cherokee Nation Health · Chickasaw Nation Health · Choctaw Nation · tribal primary care

Mid-Career NP (3-7 yrs)

$80,000–$112,000

Functional NP at OK health system · transitioning to senior band

New Grad NP (0-2 yrs)

$78,000–$98,000

OU DNP + OSU DNP + Frontier Nursing pipeline · entry band

Worth knowing: Oklahoma's substantial tribal health system NP employment is a distinctive feature most national NP-career surveys understate for the state. The Cherokee Nation Health Services (the country's largest tribal health system operating W.W. Hastings Indian Hospital Tahlequah + Cherokee Nation Outpatient Health Center + substantial regional clinic network across the 14-county Cherokee Nation reservation in NE OK, ~$1B+ annual budget + ~5K+ employees) + Chickasaw Nation Department of Health Ada + Choctaw Nation Health Services Talihina + Muscogee Creek Nation Department of Health Okmulgee combined operate substantial NP-led tribal primary care + rural clinics serving Native American patients across OK. Tribal health NPs operate under tribal sovereignty + IHS funding + collaborative practice frameworks that may differ from OK state restrictions. Senior tribal health NPs clear $95-140K TC plus substantial federal benefits + tribal benefits. OK NP practice requires collaborative practice agreement with physician (Oklahoma Code Title 59 §567.6 et seq.) — OK is a hybrid restricted framework state (not Full Practice Authority) where NPs require physician collaboration for prescriptive authority — somewhat limiting independent practice vs FPA states (OR/IA/MT/AK) but supporting substantial APP-led primary care across rural OK + tribal areas. OK joined PsyPact in 2020 supporting OK PMHNP telehealth across compact-state lines. OK's flat 4.75% + no estate tax + RTW since 2001 supports senior NP retention.

Calculate Your Exact Take-Home Pay

Add 401(k) contributions, HSA, dependents, and more to see your personalized take-home.

Open Full Calculator

Frequently Asked Questions

Find answers to common questions about your taxes and our calculator.

Compare Two States

See how income tax, take-home pay, and total tax burden differ between any two US states side by side.

State 1

State 2

Nurse Practitioner Salary in Other States

More on Oklahoma