Nurse Practitioner Salary in Oklahoma (2026)
The average Nurse Practitioner in Oklahoma earns around $138,000/year. After taxes, your estimated take-home is $99,665/year ($8,305/month).
Take-Home Pay Breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $99,665 |
Monthly Take-Home Pay | $8,305 |
Biweekly Take-Home Pay | $3,833 |
Hourly Take-Home Pay based on 2,080 hrs/year | $48/hr |
Federal Tax | $21,854 |
State Tax | $5,924 |
FICA Taxes | $10,557 |
Effective Tax Rate total taxes ÷ gross salary | 27.78% |
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Nurse Practitioner Salary Ranges in Oklahoma
Not all Nurse Practitioners earn the same — not even close
Oklahoma's nurse practitioner market is anchored by OU Health Sciences Center Oklahoma City (~14K academic medical center with substantial APP integration), Integris Health Oklahoma City (~12K largest OK health system with APP-led primary care), Saint Francis Health System Tulsa (~10K, NE OK academic + tertiary), Mercy Hospital OKC, plus substantial tribal health system APP-led primary care (Cherokee Nation Health Services + Chickasaw Nation + Choctaw Nation operating substantial NP-led rural clinics across the 14-county Cherokee Nation reservation + Chickasaw Nation reservation + Choctaw Nation reservation), OU College of Nursing + OSU College of Nursing DNP pipelines. OK requires collaborative practice agreement with physician — OK is a hybrid framework state.
Senior Specialty NP (Cardiology / Oncology)
$118,000–$180,000
OU + Integris + Saint Francis cardiology + oncology + transplant NP · OK collaborative required
Senior Psychiatric Mental Health NP
$115,000–$175,000
OU Psychiatry · Griffin Memorial Hospital · PMHNP · OK PsyPact telehealth since 2020
Senior Acute Care NP (ICU / ED)
$112,000–$170,000
OU Level 1 · Hillcrest Tulsa Level 1 · OU Critical Care · ACNP-AG subspecialty band
Senior Hospitalist NP
$110,000–$165,000
OU + Integris + Saint Francis + Mercy hospital medicine APP · day + nocturnist mix
Senior Primary Care NP (Family Medicine)
$95,000–$140,000
Integris + Saint Francis + Mercy · OK collaborative required for prescriptive authority
Senior Pediatric NP
$92,000–$135,000
Oklahoma Children's · The Children's Hospital Saint Francis · CPNP-PC + CPNP-AC
Senior Women's Health NP
$92,000–$130,000
OU WHNP · Saint Francis WomenCare · WHNP-BC
Senior Tribal Health NP (Cherokee / Chickasaw)
$95,000–$140,000
Cherokee Nation Health · Chickasaw Nation Health · Choctaw Nation · tribal primary care
Mid-Career NP (3-7 yrs)
$80,000–$112,000
Functional NP at OK health system · transitioning to senior band
New Grad NP (0-2 yrs)
$78,000–$98,000
OU DNP + OSU DNP + Frontier Nursing pipeline · entry band
Worth knowing: Oklahoma's substantial tribal health system NP employment is a distinctive feature most national NP-career surveys understate for the state. The Cherokee Nation Health Services (the country's largest tribal health system operating W.W. Hastings Indian Hospital Tahlequah + Cherokee Nation Outpatient Health Center + substantial regional clinic network across the 14-county Cherokee Nation reservation in NE OK, ~$1B+ annual budget + ~5K+ employees) + Chickasaw Nation Department of Health Ada + Choctaw Nation Health Services Talihina + Muscogee Creek Nation Department of Health Okmulgee combined operate substantial NP-led tribal primary care + rural clinics serving Native American patients across OK. Tribal health NPs operate under tribal sovereignty + IHS funding + collaborative practice frameworks that may differ from OK state restrictions. Senior tribal health NPs clear $95-140K TC plus substantial federal benefits + tribal benefits. OK NP practice requires collaborative practice agreement with physician (Oklahoma Code Title 59 §567.6 et seq.) — OK is a hybrid restricted framework state (not Full Practice Authority) where NPs require physician collaboration for prescriptive authority — somewhat limiting independent practice vs FPA states (OR/IA/MT/AK) but supporting substantial APP-led primary care across rural OK + tribal areas. OK joined PsyPact in 2020 supporting OK PMHNP telehealth across compact-state lines. OK's flat 4.75% + no estate tax + RTW since 2001 supports senior NP retention.
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More on Oklahoma
Salaries by profession, top-paying roles by industry, and an economic breakdown for Oklahoma in 2026.
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