Healthcare

Nurse Practitioner Salary in Mississippi (2026)

The average Nurse Practitioner in Mississippi earns around $138,000/year. After taxes, your estimated take-home is $100,161/year ($8,347/month).

Take-Home Pay Breakdown

CategoryAmount
Annual Take-Home Pay
$100,161
Monthly Take-Home Pay
$8,347
Biweekly Take-Home Pay
$3,852
Hourly Take-Home Pay

based on 2,080 hrs/year

$48/hr
Federal Tax
$21,854
State Tax
$5,428
FICA Taxes
$10,557
Effective Tax Rate

total taxes ÷ gross salary

27.42%
Estimates only — not tax advice. · Full disclaimer →

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Nurse Practitioner Salary Ranges in Mississippi

Entry Level (0–3 yrs)

$110,000

/year

See tax breakdown →

Mid Level (3–7 yrs)

$138,000

/year

See tax breakdown →

Senior Level (7+ yrs)

$220,000

/year

See tax breakdown →

Not all Nurse Practitioners earn the same — not even close

Mississippi's nurse practitioner market is anchored by UMMC University of Mississippi Medical Center Jackson (substantial APP workforce across the only MS academic medical center + UMC Trauma + Children's of Mississippi + UMMC Center for Telehealth), North Mississippi Health Services Tupelo (substantial NE MS APP workforce), Memorial Hospital at Gulfport + Singing River Pascagoula MS Coast APP, Forrest General Hospital Hattiesburg, plus UMMC School of Nursing FNP + AGACNP + PNP + WHNP programs + USM School of Nursing FNP + Mississippi College Department of Nursing NP programs + the substantial MS rural HPSA + FQHC + RHC + community health NP demand. MS NP regulatory framework remains REDUCED practice authority per AANP classification — MS NPs must maintain a collaborative practice agreement (CPA) with a physician for prescriptive authority + scope-of-practice work, a distinctive structural feature most national NP surveys understate for MS.

Senior CRNA (Nurse Anesthetist)

$185,000–$255,000+ TC

CRNA at UMMC + North MS Health + Memorial Gulfport + Singing River · highest MS APRN ceiling

Senior Acute Care NP (UMMC / North MS)

$118,000–$168,000+ TC

AGACNP at UMMC + North MS Health + Memorial Gulfport · high-acuity tertiary + ICU + ER + trauma

Senior FNP (Primary Care)

$95,000–$132,000+ TC

FNP at UMMC + community health + MS FQHC + RHC · primary care + CPA required for prescribing

Senior Psychiatric Mental Health NP (PMHNP)

$115,000–$162,000+ TC

PMHNP at UMMC Behavioral Health + Mississippi State Hospital Whitfield + MS Department of Mental Health

Senior Pediatric NP (PNP)

$95,000–$132,000+ TC

PNP at UMMC Children's of Mississippi + Memorial Gulfport + private MS pediatric practice

Senior Women's Health NP (WHNP)

$95,000–$132,000+ TC

WHNP at UMMC OB-GYN + Memorial + North MS Health + private MS OB-GYN groups

Senior Hospitalist NP / Surgical NP

$110,000–$158,000+ TC

Hospitalist NP + surgical NP at MS tertiary academic medical centers · cardiac + neuro + ortho

Senior FNP (Rural / MS Delta / HPSA)

$108,000–$145,000+ TC

FNP at MS FQHC + RHC + UMMC rural + MS HPSA Delta · MS NHSC scholarship + LRP eligible

Mid-Level NP (3-6 yrs)

$82,000–$115,000

Mid-career NP at MS enterprise · CPA required · transitioning to senior band

New Grad NP (0-2 yrs)

$70,000–$92,000

New grad NP · UMMC + USM + MS College NP program pipeline · entry band

Worth knowing: Mississippi's NP regulatory framework is one of the country's most distinctive REDUCED practice authority structures and a feature most national NP surveys understate for MS. MS remains classified as REDUCED practice authority per the American Association of Nurse Practitioners (AANP) state practice environment map — MS NPs must maintain a collaborative practice agreement (CPA) with a physician for prescriptive authority + must work under the supervision of the collaborating physician for scope-of-practice activities including diagnosis + treatment planning + medication prescribing, distinguishing MS from neighboring full practice authority states (OK + LA collaborative + AR reduced + KY reduced + AL collaborative + TN restricted). The Mississippi Board of Nursing has not advanced FPA legislation through the MS Legislature comparable to recent FPA reforms in OK + KS + UT despite ongoing MS Nurses Association + MS Council of Advanced Practice Nurses advocacy efforts. The UMMC APP workforce (the only MS academic medical center + the only MS MD-granting institution + ~10K employees + substantial UMMC employed NP workforce) operates substantial in-house NP recruitment + CPA management + APP credentialing supporting Magnet-pathway nursing + clinical care across UMMC University Hospital + UMC Children's + UMMC Cancer Center + UMC Trauma Center I + UMMC Center for Telehealth. Senior UMMC CRNAs clear $185-255K+ TC = the highest MS APRN compensation tier. UMMC School of Nursing + USM School of Nursing + Mississippi College Department of Nursing produce MS NP graduates. The substantial MS Delta + rural HPSA + FQHC + RHC + community health center NP demand supports substantial MS NHSC Scholarship + Loan Repayment Program eligible MS NP placements. MS flat 4.0% by 2026 + MS personal exemption $6,000 single + no state estate tax + MS RTW since 1954 + MS retirement income FULL EXEMPTION at any age.

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