Nurse Practitioner Salary in Mississippi (2026)
The average Nurse Practitioner in Mississippi earns around $138,000/year. After taxes, your estimated take-home is $100,161/year ($8,347/month).
Take-Home Pay Breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $100,161 |
Monthly Take-Home Pay | $8,347 |
Biweekly Take-Home Pay | $3,852 |
Hourly Take-Home Pay based on 2,080 hrs/year | $48/hr |
Federal Tax | $21,854 |
State Tax | $5,428 |
FICA Taxes | $10,557 |
Effective Tax Rate total taxes ÷ gross salary | 27.42% |
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Nurse Practitioner Salary Ranges in Mississippi
Not all Nurse Practitioners earn the same — not even close
Mississippi's nurse practitioner market is anchored by UMMC University of Mississippi Medical Center Jackson (substantial APP workforce across the only MS academic medical center + UMC Trauma + Children's of Mississippi + UMMC Center for Telehealth), North Mississippi Health Services Tupelo (substantial NE MS APP workforce), Memorial Hospital at Gulfport + Singing River Pascagoula MS Coast APP, Forrest General Hospital Hattiesburg, plus UMMC School of Nursing FNP + AGACNP + PNP + WHNP programs + USM School of Nursing FNP + Mississippi College Department of Nursing NP programs + the substantial MS rural HPSA + FQHC + RHC + community health NP demand. MS NP regulatory framework remains REDUCED practice authority per AANP classification — MS NPs must maintain a collaborative practice agreement (CPA) with a physician for prescriptive authority + scope-of-practice work, a distinctive structural feature most national NP surveys understate for MS.
Senior CRNA (Nurse Anesthetist)
$185,000–$255,000+ TC
CRNA at UMMC + North MS Health + Memorial Gulfport + Singing River · highest MS APRN ceiling
Senior Acute Care NP (UMMC / North MS)
$118,000–$168,000+ TC
AGACNP at UMMC + North MS Health + Memorial Gulfport · high-acuity tertiary + ICU + ER + trauma
Senior FNP (Primary Care)
$95,000–$132,000+ TC
FNP at UMMC + community health + MS FQHC + RHC · primary care + CPA required for prescribing
Senior Psychiatric Mental Health NP (PMHNP)
$115,000–$162,000+ TC
PMHNP at UMMC Behavioral Health + Mississippi State Hospital Whitfield + MS Department of Mental Health
Senior Pediatric NP (PNP)
$95,000–$132,000+ TC
PNP at UMMC Children's of Mississippi + Memorial Gulfport + private MS pediatric practice
Senior Women's Health NP (WHNP)
$95,000–$132,000+ TC
WHNP at UMMC OB-GYN + Memorial + North MS Health + private MS OB-GYN groups
Senior Hospitalist NP / Surgical NP
$110,000–$158,000+ TC
Hospitalist NP + surgical NP at MS tertiary academic medical centers · cardiac + neuro + ortho
Senior FNP (Rural / MS Delta / HPSA)
$108,000–$145,000+ TC
FNP at MS FQHC + RHC + UMMC rural + MS HPSA Delta · MS NHSC scholarship + LRP eligible
Mid-Level NP (3-6 yrs)
$82,000–$115,000
Mid-career NP at MS enterprise · CPA required · transitioning to senior band
New Grad NP (0-2 yrs)
$70,000–$92,000
New grad NP · UMMC + USM + MS College NP program pipeline · entry band
Worth knowing: Mississippi's NP regulatory framework is one of the country's most distinctive REDUCED practice authority structures and a feature most national NP surveys understate for MS. MS remains classified as REDUCED practice authority per the American Association of Nurse Practitioners (AANP) state practice environment map — MS NPs must maintain a collaborative practice agreement (CPA) with a physician for prescriptive authority + must work under the supervision of the collaborating physician for scope-of-practice activities including diagnosis + treatment planning + medication prescribing, distinguishing MS from neighboring full practice authority states (OK + LA collaborative + AR reduced + KY reduced + AL collaborative + TN restricted). The Mississippi Board of Nursing has not advanced FPA legislation through the MS Legislature comparable to recent FPA reforms in OK + KS + UT despite ongoing MS Nurses Association + MS Council of Advanced Practice Nurses advocacy efforts. The UMMC APP workforce (the only MS academic medical center + the only MS MD-granting institution + ~10K employees + substantial UMMC employed NP workforce) operates substantial in-house NP recruitment + CPA management + APP credentialing supporting Magnet-pathway nursing + clinical care across UMMC University Hospital + UMC Children's + UMMC Cancer Center + UMC Trauma Center I + UMMC Center for Telehealth. Senior UMMC CRNAs clear $185-255K+ TC = the highest MS APRN compensation tier. UMMC School of Nursing + USM School of Nursing + Mississippi College Department of Nursing produce MS NP graduates. The substantial MS Delta + rural HPSA + FQHC + RHC + community health center NP demand supports substantial MS NHSC Scholarship + Loan Repayment Program eligible MS NP placements. MS flat 4.0% by 2026 + MS personal exemption $6,000 single + no state estate tax + MS RTW since 1954 + MS retirement income FULL EXEMPTION at any age.
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Salaries by profession, top-paying roles by industry, and an economic breakdown for Mississippi in 2026.
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