AI / ML Engineer Salary in South Carolina (2026)
The average AI / ML Engineer in South Carolina earns around $220,000/year. After taxes, your estimated take-home is $151,444/year ($12,620/month).
Take-Home Pay Breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $151,444 |
Monthly Take-Home Pay | $12,620 |
Biweekly Take-Home Pay | $5,825 |
Hourly Take-Home Pay based on 2,080 hrs/year | $73/hr |
Federal Tax | $41,704 |
State Tax | $12,043 |
FICA Taxes | $14,809 |
Effective Tax Rate total taxes ÷ gross salary | 31.16% |
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Read the guideAI / ML Engineer Salary Ranges in South Carolina
Not all AI / ML Engineers earn the same — not even close
South Carolina's AI/ML engineer market is anchored by BMW Spartanburg (~11K SC employees with substantial connected vehicle + autonomous + manufacturing AI for BMW's global X-series production), BlueCross BlueShield of SC Columbia (federal healthcare AI + claims fraud + predictive risk modeling at TRICARE scale), Boeing 787 Charleston (aerospace manufacturing AI + predictive maintenance), MUSC Charleston Hollings Cancer Center clinical AI + computational genomics, Clemson University engineering AI + Watt Family Innovation Center, plus Volvo Charleston EV battery + autonomous driving development.
Principal ML Engineer / Director
$245,000–$425,000+ TC
BMW Director ML · BCBS Principal · Boeing Director ML · senior IC + leadership
Senior ML Engineer (Automotive AI)
$155,000–$235,000
BMW Spartanburg connected vehicle + autonomous · Volvo Charleston EV AI · automotive ML specialty
Senior ML Engineer (Federal Healthcare AI)
$145,000–$220,000
BCBS SC · TRICARE + CMS claims fraud + clinical decision support · federal AI specialty
Senior ML Engineer (Aerospace AI)
$155,000–$235,000
Boeing 787 Charleston · Lockheed F-16 Greenville · cleared aerospace AI · TS/SCI premium
Senior ML Engineer (Healthcare AI / MUSC)
$135,000–$200,000
MUSC Hollings Cancer Center · Prisma Health · clinical + genomics + imaging ML
Senior Research Scientist (Clemson / USC)
$135,000–$215,000
Clemson Watt Family Innovation Center + USC research · academic ML · publication track
ML Platform / MLOps Engineer
$135,000–$200,000
BMW + BCBS + Boeing MLOps platforms · model deployment + monitoring + governance specialty
Mid-Level ML Engineer (3-6 yrs)
$108,000–$155,000
Functional ML IC at SC Fortune 500 · transitioning to senior band
Junior ML Engineer (0-3 yrs)
$85,000–$118,000
Clemson CS + USC CS + College of Charleston pipeline · entry band
Senior ML Engineer (Cleared SRS)
$155,000–$245,000
Savannah River Site Aiken · DOE national lab · TS/SCI clearance premium
Worth knowing: BMW Manufacturing Co. Spartanburg's connected vehicle + autonomous AI development is one of the country's largest single-OEM automotive AI environments outside Tesla and a feature most national ML surveys understate for SC. BMW Spartanburg (BMW Group's largest global plant) operates substantial connected vehicle telematics + manufacturing AI + autonomous driving development supporting BMW's global X-series production — BMW's autonomous driving AI investments span Level 2 ADAS through eventual Level 4 development across global BMW models including X-series. Senior BMW Spartanburg ML engineers clear $155-235K TC. BlueCross BlueShield of SC Columbia operates the country's largest US private federal healthcare AI organization — substantial TRICARE + CMS claims fraud detection + predictive risk modeling + clinical decision support AI at federal contractor scale. Hollings Cancer Center at MUSC operates one of the country's 73 NCI-designated cancer center clinical AI programs including substantial computational pathology + genomics + imaging AI. Clemson University's Watt Family Innovation Center + Clemson International Center for Automotive Research (CU-ICAR) Greenville (post-2007 BMW + state of SC partnership, the country's only graduate engineering school co-located with a luxury automotive manufacturer) anchor SC automotive AI research. SC's 6.5% top bracket catches senior ML engineers at $250K+ TC but is substantially lower than OR/MN's 9.85-9.9% tops.
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More on South Carolina
Salaries by profession, top-paying roles by industry, and an economic breakdown for South Carolina in 2026.
Tax brackets, standard deductions, and take-home estimates for South Carolina in 2026.
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