Tech

AI / ML Engineer Salary in South Carolina (2026)

The average AI / ML Engineer in South Carolina earns around $220,000/year. After taxes, your estimated take-home is $151,444/year ($12,620/month).

Take-Home Pay Breakdown

CategoryAmount
Annual Take-Home Pay
$151,444
Monthly Take-Home Pay
$12,620
Biweekly Take-Home Pay
$5,825
Hourly Take-Home Pay

based on 2,080 hrs/year

$73/hr
Federal Tax
$41,704
State Tax
$12,043
FICA Taxes
$14,809
Effective Tax Rate

total taxes ÷ gross salary

31.16%
Estimates only — not tax advice. · Full disclaimer →

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AI / ML Engineer Salary Ranges in South Carolina

Entry Level (0–3 yrs)

$165,000

/year

See tax breakdown →

Mid Level (3–7 yrs)

$220,000

/year

See tax breakdown →

Senior Level (7+ yrs)

$380,000

/year

See tax breakdown →

Not all AI / ML Engineers earn the same — not even close

South Carolina's AI/ML engineer market is anchored by BMW Spartanburg (~11K SC employees with substantial connected vehicle + autonomous + manufacturing AI for BMW's global X-series production), BlueCross BlueShield of SC Columbia (federal healthcare AI + claims fraud + predictive risk modeling at TRICARE scale), Boeing 787 Charleston (aerospace manufacturing AI + predictive maintenance), MUSC Charleston Hollings Cancer Center clinical AI + computational genomics, Clemson University engineering AI + Watt Family Innovation Center, plus Volvo Charleston EV battery + autonomous driving development.

Principal ML Engineer / Director

$245,000–$425,000+ TC

BMW Director ML · BCBS Principal · Boeing Director ML · senior IC + leadership

Senior ML Engineer (Automotive AI)

$155,000–$235,000

BMW Spartanburg connected vehicle + autonomous · Volvo Charleston EV AI · automotive ML specialty

Senior ML Engineer (Federal Healthcare AI)

$145,000–$220,000

BCBS SC · TRICARE + CMS claims fraud + clinical decision support · federal AI specialty

Senior ML Engineer (Aerospace AI)

$155,000–$235,000

Boeing 787 Charleston · Lockheed F-16 Greenville · cleared aerospace AI · TS/SCI premium

Senior ML Engineer (Healthcare AI / MUSC)

$135,000–$200,000

MUSC Hollings Cancer Center · Prisma Health · clinical + genomics + imaging ML

Senior Research Scientist (Clemson / USC)

$135,000–$215,000

Clemson Watt Family Innovation Center + USC research · academic ML · publication track

ML Platform / MLOps Engineer

$135,000–$200,000

BMW + BCBS + Boeing MLOps platforms · model deployment + monitoring + governance specialty

Mid-Level ML Engineer (3-6 yrs)

$108,000–$155,000

Functional ML IC at SC Fortune 500 · transitioning to senior band

Junior ML Engineer (0-3 yrs)

$85,000–$118,000

Clemson CS + USC CS + College of Charleston pipeline · entry band

Senior ML Engineer (Cleared SRS)

$155,000–$245,000

Savannah River Site Aiken · DOE national lab · TS/SCI clearance premium

Worth knowing: BMW Manufacturing Co. Spartanburg's connected vehicle + autonomous AI development is one of the country's largest single-OEM automotive AI environments outside Tesla and a feature most national ML surveys understate for SC. BMW Spartanburg (BMW Group's largest global plant) operates substantial connected vehicle telematics + manufacturing AI + autonomous driving development supporting BMW's global X-series production — BMW's autonomous driving AI investments span Level 2 ADAS through eventual Level 4 development across global BMW models including X-series. Senior BMW Spartanburg ML engineers clear $155-235K TC. BlueCross BlueShield of SC Columbia operates the country's largest US private federal healthcare AI organization — substantial TRICARE + CMS claims fraud detection + predictive risk modeling + clinical decision support AI at federal contractor scale. Hollings Cancer Center at MUSC operates one of the country's 73 NCI-designated cancer center clinical AI programs including substantial computational pathology + genomics + imaging AI. Clemson University's Watt Family Innovation Center + Clemson International Center for Automotive Research (CU-ICAR) Greenville (post-2007 BMW + state of SC partnership, the country's only graduate engineering school co-located with a luxury automotive manufacturer) anchor SC automotive AI research. SC's 6.5% top bracket catches senior ML engineers at $250K+ TC but is substantially lower than OR/MN's 9.85-9.9% tops.

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