AI / ML Engineer Salary in South Carolina (2026)
Average AI / ML Engineer pay in South Carolina
$122,950/year
≈ $59/hour before tax
Middle 50% earn $101,880–$136,990
US average: $153,930
Source: BLS, May 2025 · Computer and Information Research Scientists
After tax (single filer)
$89,863/year
$7,489/month · effective tax rate 26.91%
- Federal $18,242
- State $5,440
- FICA $9,406
- Take-home
Pay by role in South Carolina
- Principal ML Engineer / Director$245,000–$425,000+ TC
- Senior ML Engineer (Automotive AI)$155,000–$235,000
- Senior ML Engineer (Federal Healthcare AI)$145,000–$220,000
- Senior ML Engineer (Aerospace AI)$155,000–$235,000
- Senior ML Engineer (Healthcare AI / MUSC)$135,000–$200,000
- Senior Research Scientist (Clemson / USC)$135,000–$215,000
See the full tax breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $89,863 |
Monthly Take-Home Pay | $7,489 |
Biweekly Take-Home Pay | $3,456 |
Hourly Take-Home Pay based on 2,080 hrs/year | $43/hr |
Federal Tax | $18,242 |
State Tax | $5,440 |
FICA Taxes | $9,406 |
Effective Tax Rate total taxes ÷ gross salary | 26.91% |
Not all AI / ML Engineers earn the same — not even close
South Carolina's AI/ML engineer market is anchored by BMW Spartanburg (~11K SC employees with substantial connected vehicle + autonomous + manufacturing AI for BMW's global X-series production), BlueCross BlueShield of SC Columbia (federal healthcare AI + claims fraud + predictive risk modeling at TRICARE scale), Boeing 787 Charleston (aerospace manufacturing AI + predictive maintenance), MUSC Charleston Hollings Cancer Center clinical AI + computational genomics, Clemson University engineering AI + Watt Family Innovation Center, plus Volvo Charleston EV battery + autonomous driving development.
Principal ML Engineer / Director
$245,000–$425,000+ TC
BMW Director ML · BCBS Principal · Boeing Director ML · senior IC + leadership
Senior ML Engineer (Automotive AI)
$155,000–$235,000
BMW Spartanburg connected vehicle + autonomous · Volvo Charleston EV AI · automotive ML specialty
Senior ML Engineer (Federal Healthcare AI)
$145,000–$220,000
BCBS SC · TRICARE + CMS claims fraud + clinical decision support · federal AI specialty
Senior ML Engineer (Aerospace AI)
$155,000–$235,000
Boeing 787 Charleston · Lockheed F-16 Greenville · cleared aerospace AI · TS/SCI premium
Senior ML Engineer (Healthcare AI / MUSC)
$135,000–$200,000
MUSC Hollings Cancer Center · Prisma Health · clinical + genomics + imaging ML
Senior Research Scientist (Clemson / USC)
$135,000–$215,000
Clemson Watt Family Innovation Center + USC research · academic ML · publication track
ML Platform / MLOps Engineer
$135,000–$200,000
BMW + BCBS + Boeing MLOps platforms · model deployment + monitoring + governance specialty
Mid-Level ML Engineer (3-6 yrs)
$108,000–$155,000
Functional ML IC at SC Fortune 500 · transitioning to senior band
Junior ML Engineer (0-3 yrs)
$85,000–$118,000
Clemson CS + USC CS + College of Charleston pipeline · entry band
Senior ML Engineer (Cleared SRS)
$155,000–$245,000
Savannah River Site Aiken · DOE national lab · TS/SCI clearance premium
Worth knowing: BMW Manufacturing Co. Spartanburg's connected vehicle + autonomous AI development is one of the country's largest single-OEM automotive AI environments outside Tesla and a feature most national ML surveys understate for SC. BMW Spartanburg (BMW Group's largest global plant) operates substantial connected vehicle telematics + manufacturing AI + autonomous driving development supporting BMW's global X-series production — BMW's autonomous driving AI investments span Level 2 ADAS through eventual Level 4 development across global BMW models including X-series. Senior BMW Spartanburg ML engineers clear $155-235K TC. BlueCross BlueShield of SC Columbia operates the country's largest US private federal healthcare AI organization — substantial TRICARE + CMS claims fraud detection + predictive risk modeling + clinical decision support AI at federal contractor scale. Hollings Cancer Center at MUSC operates one of the country's 73 NCI-designated cancer center clinical AI programs including substantial computational pathology + genomics + imaging AI. Clemson University's Watt Family Innovation Center + Clemson International Center for Automotive Research (CU-ICAR) Greenville (post-2007 BMW + state of SC partnership, the country's only graduate engineering school co-located with a luxury automotive manufacturer) anchor SC automotive AI research. SC's 5.21% top rate (H.4216, 2026) applies above $30,000 of SC taxable income, so it reaches nearly all senior ML engineers — and it is far below OR/MN's 9.85-9.9% tops.
Sources & Methodology
- →IRS Rev. Proc. 2025-32 — 2026 federal brackets and standard deduction
- →IRS Notice 2025-67 — 2026 retirement-plan contribution limits
- →IRS Rev. Proc. 2025-19 — 2026 HSA contribution limits
- →Social Security Administration — 2026 Social Security wage base
- →Individual income tax rates and filing information (SC Department of Revenue)
- →BLS Occupational Employment and Wage Statistics — AI / ML Engineer wage data for South Carolina
Salary figures are market estimates for AI / ML Engineers in South Carolina and vary by employer, specialty, seniority, and metro. Take-home math assumes a single filer with no dependents, the standard deduction, and South Carolina 2026 state rates. Local taxes, insurance premiums, and pre-tax contributions will move your number — run the calculator for your own situation.
Run your own numbers
- South Carolina paycheck calculator → · 401(k), HSA, dependents
- RSU calculator → · flat 22% withholding often falls short
- ISO / AMT calculator → · option exercises and AMT
- Capital-gains calculator → · long-term rates, NIIT, state tax
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More on South Carolina
Salaries by profession, top-paying roles by industry, and an economic breakdown for South Carolina in 2026.
Tax brackets, standard deductions, and take-home estimates for South Carolina in 2026.
Adjust filing status, 401(k) for your exact 2026 take-home in South Carolina.