Pharmacist Salary in Minnesota (2026)
The average Pharmacist in Minnesota earns around $138,000/year. After taxes, your estimated take-home is $97,589/year ($8,132/month).
Take-Home Pay Breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $97,589 |
Monthly Take-Home Pay | $8,132 |
Biweekly Take-Home Pay | $3,753 |
Hourly Take-Home Pay based on 2,080 hrs/year | $47/hr |
Federal Tax | $21,854 |
State Tax | $8,000 |
FICA Taxes | $10,557 |
Effective Tax Rate total taxes ÷ gross salary | 29.28% |
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Pharmacist Salary Ranges in Minnesota
Not all Pharmacists earn the same — not even close
Minnesota's pharmacist market is anchored by Mayo Clinic Rochester pharmacy services (top-2 US academic medical center pharmacy with substantial inpatient + outpatient + specialty pharmacy operations), M Health Fairview pharmacy + Allina pharmacy + HealthPartners pharmacy across the Twin Cities health systems, plus UnitedHealth Optum's OptumRx pharmacy benefits management organization (the country's largest PBM by some measures, ~25K MN UHG employees), Walgreens + CVS retail pharmacy chains, Cub Foods + Coborn's pharmacy, plus Mayo Clinic + U of MN College of Pharmacy academic.
Senior Clinical Pharmacist (Hospital)
$148,000–$185,000
Mayo + M Health + Allina + HealthPartners ICU + ED + oncology clinical pharmacy specialty
Senior Specialty Pharmacist
$135,000–$175,000
Mayo specialty + Fairview Specialty Pharmacy · oncology + transplant + HIV + REMS specialty
Senior Pharmacy Manager (Hospital)
$148,000–$195,000
Hospital pharmacy operations leadership · MN health system inpatient pharmacy
Senior PBM Clinical Pharmacist (OptumRx)
$135,000–$185,000
UnitedHealth OptumRx PBM clinical · formulary + prior auth + drug benefit design · UHG Fortune 5
Senior Pharmacy Informatics
$135,000–$195,000
Epic Willow + Cerner pharmacy informatics · MN Fortune 500 health system pharmacy IT
Senior Retail Pharmacist (Walgreens / CVS)
$125,000–$155,000
Retail pharmacy manager at Walgreens · CVS · Cub Foods + Coborn's · senior retail band
Senior Ambulatory Care / MTM
$128,000–$165,000
Allina + HealthPartners + M Health ambulatory pharmacy · MTM + anticoagulation + diabetes clinics
Mid-Career Pharmacist (3-7 yrs)
$118,000–$148,000
Functional staff pharmacist at MN health system · transitioning to senior band
New Grad PharmD (0-2 yrs)
$108,000–$128,000
U of MN College of Pharmacy (Twin Cities + Duluth) PharmD pipeline · entry band
PGY-1 / PGY-2 Residency
$52,000–$62,000
Mayo Clinic Pharmacy Residency · M Health Residency · U of MN residency · pre-clinical specialty path
Worth knowing: Mayo Clinic Rochester pharmacy services is among the most sophisticated academic medical center pharmacy programs in the country and a feature most national pharmacist-career surveys understate for MN. Mayo Clinic Pharmacy (~600+ pharmacists across the Rochester campus including substantial inpatient + ICU + ED + oncology + transplant + specialty pharmacy operations) operates one of the country's largest single-site academic medical center pharmacy enterprises. UnitedHealth Optum's OptumRx (~$95B revenue, the country's 3rd-largest PBM after CVS Caremark + Express Scripts, ~25K parent UHG MN employees) operates substantial PBM clinical pharmacy organizations supporting formulary + drug benefit design + clinical specialty pharmacy at Fortune 5 scale. U of MN College of Pharmacy operates the only PharmD-granting institution in MN (Twin Cities + Duluth campuses, ~660 PharmD students total, one of the largest US pharmacy schools by enrollment). MN's 9.85% top bracket catches senior clinical + specialty + PBM pharmacist comp at $175K+ TC. The Mayo Clinic Pharmacy Residency (PGY-1 + PGY-2 specialty) is among the most competitive US pharmacy residency programs.
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More on Minnesota
Salaries by profession, top-paying roles by industry, and an economic breakdown for Minnesota in 2026.
Tax brackets, standard deductions, and take-home estimates for Minnesota in 2026.
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