Registered Nurse Salary in South Dakota (2026)
The average Registered Nurse in South Dakota earns around $86,000/year. After taxes, your estimated take-home is $69,331/year ($5,778/month).
Take-Home Pay Breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $69,331 |
Monthly Take-Home Pay | $5,778 |
Biweekly Take-Home Pay | $2,667 |
Hourly Take-Home Pay based on 2,080 hrs/year | $33/hr |
Federal Tax | $10,090 |
State Tax | $0 |
FICA Taxes | $6,579 |
Effective Tax Rate total taxes ÷ gross salary | 19.38% |
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Registered Nurse Salary Ranges in South Dakota
Not all Registered Nurses earn the same — not even close
South Dakota's nursing market is anchored by Sanford Health Sioux Falls (largest SD-HQ multi-state ~50K + ~46 hospitals across SD + ND + MN + IA + Sanford USD Medical Center + Sanford Children's Hospital + the substantial Sanford Magnet designations), Avera Health Catholic ~20K (Avera McKennan + Avera Heart Hospital + Avera Cancer Institute + multi-state SD + IA + MN + NE), Monument Health Rapid City (substantial Western SD multi-hospital), the substantial Indian Health Service IHS SD nursing (Pine Ridge IHS + Rosebud IHS + Cheyenne River + Standing Rock IHS + Yankton + Sisseton-Wahpeton IHS hospitals + the substantial SD IHS nursing workforce + IHS Loan Repayment Program + IHS Scholarship), VA Sioux Falls + Hot Springs + Fort Meade VA, plus SD NP FPA since 2017 + NLC since 2018, USD College of Nursing + SDSU College of Nursing + Augustana Nursing pipelines.
CRNA (Sanford USD / Avera)
$195,000–$275,000+ OT
CRNA at Sanford USD + Avera + Monument · the substantial SD anesthesia + OBBBA OT applies
Senior NP (Sanford / Avera FPA)
$98,000–$138,000+ bonus
NP at Sanford + Avera + Monument · SD FPA since 2017
Senior Charge Nurse (Sanford USD / Avera)
$82,000–$118,000+ OT
Charge RN at Sanford USD + Avera McKennan + Monument · OBBBA OT applies
Senior ICU / ED RN
$75,000–$108,000+ OT
ICU + ED RN at Sanford USD Level 1 + Avera + Monument · the substantial SD acute care + OT
Senior OR RN
$72,000–$105,000+ OT
OR RN at Sanford USD + Avera + Monument · the substantial SD surgical + OT
Senior Pediatric RN (Sanford Children)
$72,000–$102,000+ OT
Sanford Children Hospital Sioux Falls · the substantial SD pediatric + OBBBA OT
Senior Oncology RN (Avera Cancer)
$75,000–$108,000+ OT
Avera Cancer Institute + Sanford Cancer Center · oncology RN + OBBBA OT applies
Senior IHS Reservation RN
$78,000–$108,000+ loan repayment
Pine Ridge + Rosebud + Cheyenne River + Standing Rock IHS · NHSC + LRP
Senior Federal Civilian RN (VA Sioux Falls)
$72,000–$108,000
VA Sioux Falls + Fort Meade + Hot Springs VA · federal civilian RN
New RN (Step 1-3 / Sanford / Avera)
$55,000–$72,000+ OT
New grad RN at Sanford + Avera + Monument residency programs · entry band + OT
Worth knowing: Sanford Health multi-state + Avera Health Catholic dual-system + Indian Health Service SD reservation nursing is one of the country's distinctive concentrated US single-state dual-system + IHS reservation nursing anchor and a feature most national nursing surveys understate for SD. Sanford Health (largest SD-HQ multi-state + ~50K + ~46 hospitals across SD + ND + MN + IA + Sanford USD Medical Center + Sanford Children's Hospital + the substantial Sanford Magnet designations) + Avera Health Catholic (~20K + Avera McKennan + Avera Heart Hospital + Avera Cancer Institute + the substantial Avera-Mayo Clinic affiliation history) supports substantial SD dual-system nursing. Senior Sanford + Avera RNs clear $72-118K+ OT. Monument Health Rapid City Western SD + the substantial Indian Health Service IHS SD nursing (Pine Ridge IHS as one of country's largest US IHS hospitals + Rosebud IHS + Cheyenne River + Standing Rock IHS + Yankton + Sisseton-Wahpeton IHS hospitals + the substantial SD IHS Loan Repayment Program + IHS Scholarship + USPHS Commissioned Corps pathway). SD NP Full Practice Authority since 2017 (SDCL Title 36 + 2017 HB 1080) + SD NLC since 2018. The 2025 No Tax on Overtime federal deduction applies through 2028. SD 0% state income tax + SD RTW since 1946 anchor the SD nursing proposition.
Sources & Methodology
- →IRS Rev. Proc. 2025-32 — 2026 federal brackets and standard deduction
- →IRS Notice 2025-67 — 2026 retirement-plan contribution limits
- →IRS Rev. Proc. 2025-19 — 2026 HSA contribution limits
- →Social Security Administration — 2026 Social Security wage base
- →BLS Occupational Employment and Wage Statistics — Registered Nurse wage data for South Dakota
Salary figures are market estimates for Registered Nurses in South Dakota and vary by employer, specialty, seniority, and metro. Take-home math assumes a single filer with no dependents, the standard deduction, and no state income tax (South Dakota levies none). Local taxes, insurance premiums, and pre-tax contributions will move your number — run the calculator for your own situation.
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More on South Dakota
Salaries by profession, top-paying roles by industry, and an economic breakdown for South Dakota in 2026.
Tax brackets, standard deductions, and take-home estimates for South Dakota in 2026.
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