Healthcare

Registered Nurse Salary in Oklahoma (2026)

The average Registered Nurse in Oklahoma earns around $86,000/year. After taxes, your estimated take-home is $65,747/year ($5,479/month).

Take-Home Pay Breakdown

CategoryAmount
Annual Take-Home Pay
$65,747
Monthly Take-Home Pay
$5,479
Biweekly Take-Home Pay
$2,529
Hourly Take-Home Pay

based on 2,080 hrs/year

$32/hr
Federal Tax
$10,090
State Tax
$3,584
FICA Taxes
$6,579
Effective Tax Rate

total taxes ÷ gross salary

23.55%
Estimates only — not tax advice. · Full disclaimer →

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Key terms:···

Registered Nurse Salary Ranges in Oklahoma

Entry Level (0–3 yrs)

$67,000

/year

See tax breakdown →

Mid Level (3–7 yrs)

$86,000

/year

See tax breakdown →

Senior Level (7+ yrs)

$133,000

/year

See tax breakdown →

Not all Registered Nurses earn the same — not even close

Oklahoma's nurse market is anchored by OU Health Sciences Center Oklahoma City (~14K academic medical center with substantial Magnet nursing program), Oklahoma Children's Hospital (academic pediatric Magnet), Integris Health Oklahoma City (~12K, largest OK health system by employee count, multi-Magnet hospital network), Saint Francis Health System Tulsa (~10K, largest Tulsa system), Mercy Hospital Oklahoma City + St. Anthony OKC, Hillcrest Healthcare Tulsa + Hillcrest Medical Tulsa, plus OU College of Nursing + OSU College of Nursing + TU School of Nursing + UCO Nursing pipelines.

Senior CRNA (Anesthesia)

$195,000–$305,000

OU + Integris + Saint Francis + Mercy CRNA · OK CRNA full practice · highest non-MD pay

Senior Nurse Practitioner (Specialty)

$112,000–$175,000

Cardiology + oncology + transplant NP · OU + Integris · OK NP hybrid framework

Senior Nurse Anesthetist Manager

$175,000–$275,000

CRNA team lead at OU + academic medical centers · senior CRNA leadership

Senior ICU / Critical Care RN

$85,000–$125,000

OU + Saint Francis + Integris ICU · Level 1 trauma + transplant ICU senior

Senior OR Circulating / Scrub RN

$82,000–$120,000

OU + Saint Francis + Integris OR · transplant + cardiothoracic + neuro OR specialty

Senior ED RN (Level 1 Trauma)

$85,000–$125,000

OU Level 1 adult trauma · Hillcrest Medical Tulsa Level 1 · OU Children's Level 1 pediatric

Senior Medical-Surgical RN

$68,000–$98,000

Med-surg unit RN at OK Magnet hospital · senior staff band

Senior Pediatric / NICU RN

$78,000–$115,000

Oklahoma Children's · The Children's Hospital Saint Francis · pediatric + neonatal specialty

Mid-Career RN (3-7 yrs)

$62,000–$85,000

Functional staff RN at OK Magnet hospital · transitioning to senior band

New Grad RN (0-2 yrs)

$55,000–$70,000

OU College of Nursing + OSU CON + TU SON + UCO Nursing pipeline

Worth knowing: Oklahoma's substantial Native American Indian Health Service + tribal health system nursing employment is a distinctive feature most national nursing-career surveys understate for OK. OK is home to 39 federally recognized Native American tribes — the most of any state — supporting substantial tribal health system + Indian Health Service nursing employment including Cherokee Nation Health Services (the largest tribal health system in the country, operating W.W. Hastings Indian Hospital Tahlequah + Cherokee Nation Outpatient Health Center + substantial regional clinic network across the 14-county Cherokee Nation reservation in NE OK), Chickasaw Nation Department of Health (Carl Albert Indian Hospital Ada + substantial outpatient clinic network), Choctaw Nation Health Services, Muscogee Creek Nation Department of Health, plus IHS Oklahoma City Area Office facilities. Senior tribal health + IHS RNs at $85-125K TC with substantial federal benefits. OU College of Nursing (founded 1911, ~600 BSN + MSN + DNP + PhD students, the largest AL nursing school) operates substantial nursing pipeline. OU Health operates the largest single-state Magnet recognition program in OK + Integris Health + Saint Francis Tulsa anchor OK community + suburban nursing. OK is RTW since 2001 + ~5% union density (among lowest US) — OK Nurses Association operates as professional advocacy with limited collective bargaining. OK does NOT have NP Full Practice Authority — OK requires collaborative practice agreement with physician (hybrid restricted framework). OK's flat 4.75% + no estate tax + RTW + lower cost of living supports senior RN retention.

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