Registered Nurse Salary in Mississippi (2026)
Average Registered Nurse pay in Mississippi
$78,950/year
≈ $38/hour before tax
After tax (single filer)
$61,945/year
$5,162/month · effective tax rate 21.54%
- Federal $8,539
- State $2,426
- FICA $6,040
- Take-home
Pay by role in Mississippi
- CRNA (Nurse Anesthetist)BLS · 75th–90th percentile$264,310–$281,010
- Senior / Charge RNBLS · 75th–90th percentile$84,500–$100,350
- Nurse ManagerBLS · 75th–90th percentile$126,000–$166,640
- Staff RN (early career)BLS · 10th–25th percentile$60,610–$64,930
See the full tax breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $61,945 |
Monthly Take-Home Pay | $5,162 |
Biweekly Take-Home Pay | $2,383 |
Hourly Take-Home Pay based on 2,080 hrs/year | $30/hr |
Federal Tax | $8,539 |
State Tax | $2,426 |
FICA Taxes | $6,040 |
Effective Tax Rate total taxes ÷ gross salary | 21.54% |
Not all Registered Nurses earn the same — not even close
Mississippi's RN market is anchored by UMMC University of Mississippi Medical Center Jackson (the only MS academic medical center + the only MS UMC Trauma Center I + only MS Children's of Mississippi + ~10K employees + substantial Magnet-pathway nurse workforce), Memorial Hospital at Gulfport (the largest MS Coast hospital), North Mississippi Health Services Tupelo (the largest MS health system by some employee measures + Magnet-designated), Singing River Health System Pascagoula + Ocean Springs, Forrest General Hospital Hattiesburg, Mississippi Baptist Health Systems Jackson, plus the substantial MS Delta + rural HPSA + FQHC + community health center RN demand + UMMC School of Nursing + USM School of Nursing + Mississippi College Department of Nursing + MS community college ADN pipelines + Jackson State University BSN + Delta State University BSN.
CRNA (Nurse Anesthetist)
$264,310–$281,010
CRNA at UMMC + North MS Health + Memorial Gulfport + Singing River · highest MS RN ceiling
Source: BLS May 2025 · Nurse Anesthetists · Mississippi · 75th–90th percentile
Senior / Charge RN
$84,500–$100,350
NICU + PICU at UMMC Children's of Mississippi + Memorial Gulfport
Source: BLS May 2025 · Registered Nurses · Mississippi · 75th–90th percentile
Nurse Manager
$126,000–$166,640
Nurse manager at MS Magnet + tertiary hospitals · unit + service line leadership
Source: BLS May 2025 · Medical and Health Services Managers · Mississippi · 75th–90th percentile
Staff RN (early career)
$60,610–$64,930
New grad RN · UMMC School of Nursing + USM + MS College + JSU + Delta State pipeline · entry band
Source: BLS May 2025 · Registered Nurses · Mississippi · 10th–25th percentile
Worth knowing: Mississippi's substantial post-Hurricane Katrina + Camille hurricane response training + experience is a distinctive structural feature of MS nursing most national RN surveys understate for the state. MS substantial coastal hurricane exposure (the substantial MS Coast exposure to Hurricane Katrina Aug 2005 + Category 3 at MS landfall + ~$125B+ MS Coast damage + Hurricane Camille Aug 1969 + Category 5 + the most intense US Gulf Coast hurricane at MS landfall + Hurricane Frederic 1979 + Hurricane Elena 1985 + Hurricane Georges 1998 + the substantial ongoing MS coastal hurricane response readiness) supports substantial seasonal MS RN hurricane surge + crisis travel rate work clearing $2,400-3,800+/wk at peak surge periods. UMMC (the only MS academic medical center + the only MS MD-granting institution + UMC Trauma Center I + Children's of Mississippi + ~10K employees + substantial Magnet-pathway nursing workforce) operates substantial in-house Magnet-pathway + academic + tertiary nursing across UMMC University Hospital + UMC Children's + UMMC Cancer Center. Senior UMMC Magnet RNs + Charge Nurses + Nurse Managers clear $78-132K+. North Mississippi Health Services Tupelo (~7K employees + the largest MS health system by some measures + Magnet-designated) supports substantial NE MS regional nursing. Memorial Hospital at Gulfport (the largest MS Coast hospital) + Singing River Health System Pascagoula + Ocean Springs support substantial MS Coast nursing serving Ingalls Pascagoula occupational + Keesler AFB MTF referrals + Biloxi-Gulfport gaming workforce + the substantial Gulf Coast post-disaster population. MS is a Nurse Licensure Compact (NLC) state since 2001 (the country's first US NLC state alongside MD + NC + TX + WI) supporting MS RN practice across all 41+ NLC states. MS NP regulatory framework — MS remains REDUCED practice authority per AANP classification (collaborative practice agreement required for prescriptive authority — see nurse-practitioner entry). MS flat 4.0% by 2026 + MS personal exemption $6,000 single + no state estate tax + MS RTW since 1954 + MS retirement income FULL EXEMPTION + lower MS Coast + Jackson + Tupelo cost of living anchor the MS RN proposition.
Sources & Methodology
- →IRS Rev. Proc. 2025-32 — 2026 federal brackets and standard deduction
- →IRS Notice 2025-67 — 2026 retirement-plan contribution limits
- →IRS Rev. Proc. 2025-19 — 2026 HSA contribution limits
- →Social Security Administration — 2026 Social Security wage base
- →MS DOR Publication 89-700, rev. 13 January 2026 - the Exemptions and Deductions Schedule ($6,000/$9,500/$12,000 exemption beside a $2,300/$3,400/$4,600 standard deduction) and the Tax Year 2026 rate table (first $10,000 at 0%, balance at 4.0%)
- →BLS Occupational Employment and Wage Statistics — Registered Nurse wage data for Mississippi
Salary figures are market estimates for Registered Nurses in Mississippi and vary by employer, specialty, seniority, and metro. Take-home math assumes a single filer with no dependents, the standard deduction, and Mississippi 2026 state rates. Local taxes, insurance premiums, and pre-tax contributions will move your number — run the calculator for your own situation.
Run your own numbers
- Mississippi paycheck calculator → · 401(k), HSA, dependents
- No Tax on Overtime calculator → · up to $12,500 off federal tax
- Bonus calculator → · year-end, sign-on, retention
- 1099 tax calculator → · self-employment tax 15.3%
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More on Mississippi
Salaries by profession, top-paying roles by industry, and an economic breakdown for Mississippi in 2026.
Tax brackets, standard deductions, and take-home estimates for Mississippi in 2026.
Adjust filing status, 401(k) for your exact 2026 take-home in Mississippi.