How much does a Registered Nurse make in Minnesota?

BLS puts the average Registered Nurse pay in Minnesota at $103,420 a year (BLS, May 2025). On that pay in Minnesota, after federal taxes, FICA, and Minnesota state taxes, your estimated take-home pay is approximately $76,077 annually ($6,340/month).

What is the take-home pay for a Registered Nurse in Minnesota?

On a $103,420 salary in Minnesota, your take-home pay is approximately $76,077/year or $6,340/month. Federal tax: $13,922. State tax: $5,509. FICA: $7,912.

Is $103,420 a good Registered Nurse salary?

$103,420 is the BLS average Registered Nurse pay in Minnesota, about the same as the US average of $101,420 (BLS, May 2025). The middle 50% in Minnesota earn between $88,940 and $114,760.

How do Minnesota taxes affect Registered Nurse salaries?

Minnesota levies state income tax on top of federal taxes. Your estimated state tax on $103,420 is $5,509. Your total effective tax rate is approximately 26.4%.

What are the career growth prospects for Registered Nurses?

In Minnesota, the top 10% earn over $132,430 and the bottom 10% under $79,960 (BLS, May 2025). 6% growth through 2032 (faster than average). Related roles include: LPN, Nurse Practitioner, Travel Nurse, ICU Nurse.

How can a Registered Nurse in Minnesota reduce their tax bill?

Maximize your 401(k) contribution ($24,500 in 2026) to reduce taxable income. An HSA ($4,400 single / $8,750 family) adds further pre-tax savings. These strategies can save thousands annually — use our calculator to see your exact savings.

Healthcare

Registered Nurse Salary in Minnesota (2026)

Average Registered Nurse pay in Minnesota

$103,420/year

≈ $50/hour before tax

Middle 50% earn $88,940–$114,760

US average: $101,420

Source: BLS, May 2025

After tax (single filer)

$76,077/year

$6,340/month · effective tax rate 26.44%

Federal $13,922
State $5,509
FICA $7,912
Take-home

Pay by role in Minnesota

CRNA (Nurse Anesthetist)BLS · 75th–90th percentile$272,980–$292,200
Nurse PractitionerBLS · 75th–90th percentile$155,260–$170,140
Nurse ManagerBLS · 75th–90th percentile$151,740–$196,830
Senior / Charge RNBLS · 75th–90th percentile$114,760–$132,430
Staff RN (all units)BLS · middle 50%$88,940–$114,760
Staff RN (early career)BLS · 10th–25th percentile$79,960–$88,940

See the full tax breakdown

Category	Amount
Annual Take-Home Pay	$76,077
Monthly Take-Home Pay	$6,340
Biweekly Take-Home Pay	$2,926
Hourly Take-Home Pay based on 2,080 hrs/year	$37/hr
Federal Tax	$13,922
State Tax	$5,509
FICA Taxes	$7,912
Effective Tax Rate total taxes ÷ gross salary	26.44%

Estimates only — not tax advice. · Full disclaimer →

Not all Registered Nurses earn the same — not even close

Minnesota's nurse market is anchored by Mayo Clinic Rochester (~70K MN employees including ~14K MN RNs, the country's largest single-state academic medical center nurse employer), M Health Fairview (~37K employees integrating U of MN with Fairview hospitals + 8 Twin Cities + regional hospitals), Allina Health Minneapolis (~30K, Abbott Northwestern + Mercy + United + 12 hospitals), HealthPartners Bloomington (~26K, Regions + Methodist + 8 hospitals + integrated payer), Children's Minnesota (Mpls + St. Paul pediatric Magnet), HCMC (safety-net Level 1 trauma), plus Essentia + CentraCare regional.

CRNA (Nurse Anesthetist)

$272,980–$292,200

Mayo + M Health + Allina + HealthPartners CRNA · MN Full Practice CRNA · highest non-MD pay

Source: BLS May 2025 · Nurse Anesthetists · Minnesota · 75th–90th percentile

Nurse Practitioner

$155,260–$170,140

Cardiology + oncology + transplant NP · Mayo + M Health · Full Practice Authority since 2014

Source: BLS May 2025 · Nurse Practitioners · Minnesota · 75th–90th percentile

Nurse Manager

$151,740–$196,830

CRNA team lead at Mayo + academic medical centers · senior CRNA leadership

Source: BLS May 2025 · Medical and Health Services Managers · Minnesota · 75th–90th percentile

Senior / Charge RN

$114,760–$132,430

Mayo + M Health + Abbott Northwestern ICU · Level 1 trauma + transplant ICU senior

Source: BLS May 2025 · Registered Nurses · Minnesota · 75th–90th percentile

Staff RN (all units)

$88,940–$114,760

Functional staff RN at MN Magnet hospital · transitioning to senior band

Source: BLS May 2025 · Registered Nurses · Minnesota · middle 50%

Staff RN (early career)

$79,960–$88,940

U of MN School of Nursing + St. Catherine + Bethel + Concordia + St. Olaf nursing pipeline

Source: BLS May 2025 · Registered Nurses · Minnesota · 10th–25th percentile

Worth knowing: Mayo Clinic Rochester is the largest single-state academic medical center nurse employer in the country and a feature most national nursing-career surveys understate for MN. Mayo Clinic employs ~14K MN registered nurses (within ~70K total MN employees), supporting one of the country's most comprehensive academic medical center nursing programs across cardiac + transplant + oncology + neuro + pediatric subspecialty. Mayo Clinic was an early adopter of the Magnet recognition program. MN granted Nurse Practitioners Full Practice Authority via SF 2545 of 2014 — among the earlier US states to grant FPA, meaning MN NPs can prescribe + practice independently without physician collaboration agreements, supporting senior NP comp at $135-215K TC and substantial NP-led primary care practice across rural MN. Minnesota Nurses Association (MNA, ~22K members affiliated with National Nurses United) is one of the country's most active nursing unions — the 2022 MNA strike across 7 hospital systems was the largest US private-sector nurses strike, supporting strong MN RN comp + benefits + staffing-ratio bargaining. MN's 9.85% top bracket catches CRNA + senior NP comp at $200K+ TC.

Sources & Methodology

Salary figures are market estimates for Registered Nurses in Minnesota and vary by employer, specialty, seniority, and metro. Take-home math assumes a single filer with no dependents, the standard deduction, and Minnesota 2026 state rates. Local taxes, insurance premiums, and pre-tax contributions will move your number — run the calculator for your own situation.

Run your own numbers