Registered Nurse Salary in Minnesota (2026)
The average Registered Nurse in Minnesota earns around $86,000/year. After taxes, your estimated take-home is $65,006/year ($5,417/month).
Take-Home Pay Breakdown
| Category | Amount |
|---|---|
Annual Take-Home Pay | $65,006 |
Monthly Take-Home Pay | $5,417 |
Biweekly Take-Home Pay | $2,500 |
Hourly Take-Home Pay based on 2,080 hrs/year | $31/hr |
Federal Tax | $10,090 |
State Tax | $4,325 |
FICA Taxes | $6,579 |
Effective Tax Rate total taxes ÷ gross salary | 24.41% |
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Registered Nurse Salary Ranges in Minnesota
Not all Registered Nurses earn the same — not even close
Minnesota's nurse market is anchored by Mayo Clinic Rochester (~70K MN employees including ~14K MN RNs, the country's largest single-state academic medical center nurse employer), M Health Fairview (~37K employees integrating U of MN with Fairview hospitals + 8 Twin Cities + regional hospitals), Allina Health Minneapolis (~30K, Abbott Northwestern + Mercy + United + 12 hospitals), HealthPartners Bloomington (~26K, Regions + Methodist + 8 hospitals + integrated payer), Children's Minnesota (Mpls + St. Paul pediatric Magnet), HCMC (safety-net Level 1 trauma), plus Essentia + CentraCare regional.
Senior CRNA (Anesthesia)
$245,000–$365,000
Mayo + M Health + Allina + HealthPartners CRNA · MN Full Practice CRNA · highest non-MD pay
Senior Nurse Practitioner (Specialty)
$135,000–$215,000
Cardiology + oncology + transplant NP · Mayo + M Health · Full Practice Authority since 2014
Senior Nurse Anesthetist Manager
$215,000–$325,000
CRNA team lead at Mayo + academic medical centers · senior CRNA leadership
Senior ICU / Critical Care RN
$108,000–$155,000
Mayo + M Health + Abbott Northwestern ICU · Level 1 trauma + transplant ICU senior
Senior OR Circulating / Scrub RN
$105,000–$148,000
Mayo Surgery + M Health OR · transplant + cardiothoracic + neuro OR specialty
Senior ED RN (Level 1 Trauma)
$105,000–$148,000
HCMC Level 1 · Regions Level 1 · North Memorial Level 1 · trauma + stroke + STEMI center
Senior Medical-Surgical RN
$92,000–$128,000
Med-surg unit RN at Mayo + Twin Cities Magnet hospitals · senior staff band
Senior Pediatric / NICU RN
$98,000–$138,000
Children's MN · M Health Masonic Children's · Mayo NICU · pediatric + neonatal specialty
Mid-Career RN (3-7 yrs)
$82,000–$108,000
Functional staff RN at MN Magnet hospital · transitioning to senior band
New Grad RN (0-2 yrs)
$72,000–$88,000
U of MN School of Nursing + St. Catherine + Bethel + Concordia + St. Olaf nursing pipeline
Worth knowing: Mayo Clinic Rochester is the largest single-state academic medical center nurse employer in the country and a feature most national nursing-career surveys understate for MN. Mayo Clinic employs ~14K MN registered nurses (within ~70K total MN employees), supporting one of the country's most comprehensive academic medical center nursing programs across cardiac + transplant + oncology + neuro + pediatric subspecialty. Mayo Clinic was an early adopter of the Magnet recognition program. MN granted Nurse Practitioners Full Practice Authority via SF 2545 of 2014 — among the earlier US states to grant FPA, meaning MN NPs can prescribe + practice independently without physician collaboration agreements, supporting senior NP comp at $135-215K TC and substantial NP-led primary care practice across rural MN. Minnesota Nurses Association (MNA, ~22K members affiliated with National Nurses United) is one of the country's most active nursing unions — the 2022 MNA strike across 7 hospital systems was the largest US private-sector nurses strike, supporting strong MN RN comp + benefits + staffing-ratio bargaining. MN's 9.85% top bracket catches CRNA + senior NP comp at $200K+ TC.
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More on Minnesota
Salaries by profession, top-paying roles by industry, and an economic breakdown for Minnesota in 2026.
Tax brackets, standard deductions, and take-home estimates for Minnesota in 2026.
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